Bioactivity and chemical constituents of Rhoeo discolor.
Associate Professor Lim Yau Yan
Building/Room: Building 3, Level 4, Lab 11
Rhoeo discolour is a common ornamental plant from the Commelinaceae (spiderwort) family that has been used in traditional medicine for the treatment of superficial mycoses, particularly in South America by the ancient Mayan culture.
The bioactivity of the plant extracts (partially purified fractions from activity-guided fractionation and isolated compounds) would be assessed in several ways:
Antioxidant activity testing - total phenolic and flavonoid content, free radical reducing activities, ferric reducing activities, beta carotene bleaching
Antibacterial and antifungal activity.
Cytotoxicity testing on normal and cancerous cell lines.
The samples would be subjected to HPLC analysis; chromatographic isolation and compounds identification via LC-MS and NMR.
Chan, E.W.C., Lim, Y.Y., Chong, K.L., Tan, J.B.L. and Wong, S.K. (2009) Antioxidant Properties of Tropical and Temperate Herbal Teas, Journal of Food Composition and Analysis (Accepted).