Associate Professor Song Keang Peng

Associate Professor and Head of School

PhD ( Texas Tech University Health Sciences Center, USA)

Telephone: +603 - 5514 6094
Fax: +603 - 5514 6099
E-mail: song.keang.peng@artsci.monash.edu.my

Links:

Area of Expertise
Research Interest
Selected Journals
Book Chapters
Current Research Projects
Prospective Research Projects
Research Students
Research Assistant

Microbiology, molecular biology

Molecular pathogenesis of bacterial diseases, regulation of bacterial toxin expression, epidemiology and pathogenesis of periodontal diseases.

Goh S, Ong PF, Song KP, Riley TV, Chang BJ (2007) The complete genome sequence of Clostridium difficile phage C2 and comparisons to CD119 and inducible prophages of CD630. Microbiology ( UK). 153: 676-685.

Koh TH, Tan AL, Wang G and Song KP (2007) Epidemiology of Clostridium difficile infection in a large teaching hospital in Singapore. Pathology. 39:438-442

George S, Kishen A, Song KP (2005) Investigation on the role of environmental changes on monospecies biofilm formation on root canal wall by Enterococcus faecalis. Journal of Endodontics. 31:867-872.

Lee ASY, Song KP (2005) LuxS/Autoinducer-2 (AI-2) quorum sensing molecule regulates transcriptional virulence genes expression in Clostridium difficile. Biochemical and Biophysical Research Communications 335: 659-666.

Tan KS, Ong G, Song KP (2005) Introns in cytolethal distending toxin gene of Actinobacillus actinomycetemcomitans. Journal of Bacteriology 187: 567-575.

Angeles DC , Song KP (2005) Peptide antibiotic and actin-binding protein as mixed-type inhibitors of Clostridium difficile CDT toxin activities. Biochemical and Biophysical Research Communications 327: 361-370.

Lui JN, Sae-Lim V, Song KP, Chen NN (2004) In vitro antimicrobial effect of chlorhexidine-impregnated gutta percha points on Enterococcus faecalis. International Endodontic Journal 43:105-113.

Yeo CC, Wong MV, Song KP and Poh CL. Molecular characterization of an inducible gentisate 1, 2-dioxygenase gene, xlnE, from Pseudomonas alcaligenes NCIB 9867. 2003. Gene. 312:239-248

Cheng CL, Song KP, Chee SP, Chan TK (2002) PCR-aided diagnosis of fungal chorioretinitis following ingestion of traditional chinese medication. 2002. The Journal of Retinal and Vitreous Diseases 22:803-806.

Tan KS, Song KP, Ong G (2002) Cytolethal distending toxin of Actinobacillus actinomycetemcomitans: Occurrence and association with periodontal disease. Journal of Periodontal Research 37:268-272.

Tan KS, Woo CH, Ong G, Song KP (2001) Prevalence of Actinobacillus actinomycetemcomitans in an ethnic adult Chinese population. Journal of Clinical Periodontology 28:886-890.

Tan KS, Song KP, Ong G (2001) Bacteroides forsythus prtH genotype in periodontitis patients: Occurrence and association with periodontal disease. Journal of Periodontal Research 36:398-403.

Tan KS, Wee BY, Song KP (2001) Evidence for holing-function of tcdE gene in pathogenesis of Clostridium difficile. Journal of Medical Microbiology 50:613-619.

Chow TK, Inglis TJJ, Song KP (2006) Microbes in medical biotechnology. In Microbial Biotechnology: Principles and Applications (2nd ed). Lee YK (Ed). World Scientific Publishing. pp 537-622

• Molecular cloning, expression and characterization of fibroblast-activating factor from Porphyromonas gingivalis

• Epidemiology and molecular analysis of antibiotic-associated diarrhea.
• Characterization of introns in pathogenic genes of oral pathogens.

Honours students: (Present)

Leong Wai Khay - Regulation of hmuY gene expression in Porphyromonasgingivalis. 2008.

Poh Boon Min - Differential expression of hmuY in the periodontopathogenic Porphyromonas gingivalis under various cultural conditions. 2008.

Felicia Paulraj - Long-lasting effects of postnatal selective serotonin reuptake inhibitor treatment on schizophrenic-like behavior and sexual dysfunction. (a collaborative project with Prof Ishwar Parhar of the Brain Research Institute, Sunway Campus)

Honours Students: (Past)

Mak Tim Nam - Molecular characterization of fibroblast-activating factor from Porphyromonas gingivalis. 2007.

Tan Yun Ying - Development of vaccine delivery vector using C-terminal repeat region of toxin A/B of Clostridium difficile. 2007.

Tan Sue Ann - The effects of curcumin and NS398 on increasing the efficacy of photodynamic therapy in human cancer cell lines. 2007. (a collaborative project with Dr Eswary Thirthagiri of the Cancer Research Initiatives Foundation)

PhD student: ( Present )

How Kah Yan - Molecular cloning, expression and characterization of fibroblast-activating factor from Porphyromonas gingivalis.

Leong Wai Khay - Identification and characterization of regulator(s) for the expression of hmuY gene of Porphyromonas gingivalis.